Trimethobenzamide (HCl)

Drug #1495

A dopamine blocker , which has weak antihistaminic activity. It is given for the treatment and prevention of nausea and vomiting. Major adverse effects include restlessness, dystonia, and parkinsonian symptoms.

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Primary Characteristics

It is of Synthetic origin.

Molecular Weight: 424.9 · Solubility in Water: 1 in 2 · Solubility in Alcohol: 1 in 59 · Non-proprietary name: Trimethobenzamide (HCl).

Molecular structure of Trimethobenzamide (HCl)

Pharmacokinetics

None recorded.

Indications

Trimethobenzamide (HCl) is primarily indicated in conditions like Nausea and vomiting.

Contraindications

None recorded.

Dosage

None recorded.

Drug Interactions

Unknown1 interaction

2 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Trimethobenzamide (HCl) in overdosage may give rise to further complications which include Cardiac arrhythmias, Blood disorders , Convulsions , CNS depression, Paresthesia.

Trimethobenzamide (HCl) is known to cause more or less tolerable side effects which are usually transient. These include Angioedema, Blurred vision, Bronchospasm, Diarrhea, Dry mouth, Epigastric pain, Headache, Local irritation, Nausea and vomiting, Pain at injection site.

Warnings / Precautions

It should be used with caution in patients with any eye problems, high blood pressure, diabetes, thyroid disorder, heart disease, asthma or allergies, especially to sulfites. Use with caution during pregnancy or lactation.

Available Brands

None recorded.

Storage Conditions

Trimethobenzamide (HCl) should be stored Cap, Inj .

Drug Classification

1.17.2 — Antiemetics & antinauseants