Bunazosin (HCl)

Drug #1435

Primary Characteristics

It is of Synthetic origin and belongs to Diazepine.

Molecular Weight: 410 · pK_a: 7.7 · Solubility in Water: 1 in 35 · Solubility in Alcohol: very slightly · Non-proprietary name: Bunazosin (HCl).

Pharmacokinetics

Elimination: plasma half-life is 1.5 ± 0.2 hr.

Indications

Bunazosin (HCl) is primarily indicated in conditions like Essential hypertension, Phaeochromocytoma, Renal hypertension.

Contraindications

Bunazosin (HCl) is contraindicated in conditions like Orthostatic hypotension, Hypersensitivity.

Dosage

None recorded.

Drug Interactions

None recorded.

Side Effects

Bunazosin (HCl) in overdosage may give rise to further complications which include Orthostatic hypotension , Palpitation , Aggravation of angina, Tachycardia , Orthostatic syncope.

Bunazosin (HCl) is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Cold or profused sweating, Constipation , Diarrhea, Dizziness, Dry mouth, Headache, Heavy headedness, Light headedness, Nausea, Vertigo.

Warnings / Precautions

Avoid use of bunazosin in neonates and during pregnancy. Because of the greater likelihood of orthostatic hypotension in elderly patients, bunazosin therapy should be started with caution. A low dose should be administered initially and this may be gradually increased depending on patients response and with careful checking of the standing blood pressure.

Available Brands

None recorded.

Storage Conditions

Bunazosin (HCl) should be stored Tab.

Drug Classification

1.12.3.5 — Alpha-1 receptor antagonists