Magnesium Trisilicate
Magnesium Trisilicate is a non-systemic antacid used in the treatment of peptic ulceration. Neutralization of acid is slow in onset but relatively prolonged due to adsorbent properties of silicic acid formed in the stomach. It has a lexative effect in larger doses. Danger of magnesium toxicity in patients with renal failure.
Primary Characteristics
Molecular Weight: 260.9 · Solubility in Water: Insoluble · Solubility in Alcohol: Insoluble · Non-proprietary name: Magnesium Trisilicate.
Pharmacokinetics
Distribution: Magnesium Trisilicate has a plasma protein binding is one third.
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Indications
Magnesium Trisilicate is primarily indicated in conditions like Dyspepsia, Heart burn, Hyperacidity.
Contraindications
Magnesium Trisilicate is contraindicated in conditions like Osteomalacia, Hypophosphataemia, Kidney disease.
Dosage
Magnesium Trisilicate's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 500 ml | 500 ml | — | PO | As required |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Magnesium Trisilicate in overdosage may give rise to further complications which include Hypermanganesemia, Kidney stones.
Magnesium Trisilicate is known to cause more or less tolerable side effects which are usually transient. These include Constipation , Diarrhea, Nausea and vomiting.
Warnings / Precautions
Available Brands
Storage Conditions
Drug Classification
- 1.17.1.1 — Antacids & antiflatulents