Theobromine
Theobromine is alkaloid prepared from the dried ripe seed of Theobroma cacao or made synthetically from xanthine. It has physiologic properties similar to those of caffeine. its major source is beverages (tea, cocoa and coffee). Chemically Theobromine is 3, 7-dimethylxanthine. It can be employed as a diuretic, it acts by inhibiting reabsorption of sodium and chloride in the renal tubules. Theobromine is less toxic, and thus can be employed on occasions when the more toxic diuretics are contraindicated such as when renal function is poor. The wide choice of more effective diuretics has limited the use of it as a diuretic. It dilates the coronary arteries and increase the coronary blood flow.
Primary Characteristics
It is of Natural origin.
Solubility in Water: very slightly soluble · Solubility in Alcohol: very slightly soluble · Non-proprietary name: Theobromine.

Pharmacokinetics
None recorded.
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Indications
Theobromine is primarily indicated in conditions like Diuresis.
Theobromine is also indicated for secondary conditions like Hypertension.
Contraindications
Theobromine is contraindicated in conditions like Hypersensitivity.
Dosage
None recorded.
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Theobromine is known to cause more or less tolerable side effects which are usually transient. These include Anxiety, Loss of appetite, Nausea and vomiting, Restlessness, Sleeplessness, Tremors.
Warnings / Precautions
Available Brands
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Multi-Ingredient Combinations
Storage Conditions
Drug Classification
- 1.7.1 — Acute migraine attack
- 2.25.1.1 — Oral/Parenteral antiasthmatics
Manufacturers
Manufacturers of Theobromine in Pakistan: