DrugInfoSys

Glycine

Also known as: Aminoethonoic Acid, 2-Aminoacetic acid

Drug #1299

Glycine is the smallest of the amino acids, non-essential amino acid occuring as a constituents of many proteins. Chemically itaminoacetic acid. It is a glycogenic and participates in variety of synthetic reactions. Glycine is used with antacid in stomach hyperacidity, also with aspirin to reduce its stomach irritation.

Primary Characteristics

Glycine is also known as Aminoethonoic Acid, 2-Aminoacetic acid.

It is of Synthetic origin and belongs to Aminoacid.

Molecular Weight: 75.05 · Solubility in Water: 1 in 4 · Solubility in Alcohol: 1 in 1254 · Non-proprietary name: Glycine.

Molecular structure of Glycine

Pharmacokinetics

Elimination: it is metabolised via hepatic.

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Indications

Glycine is primarily indicated in conditions like Bladder irrigation, Urogenital tract inflammation.

Glycine is also indicated for secondary conditions like Hyperacidity.

Contraindications

Glycine is contraindicated in conditions like Anuria.

Dosage

Glycine's dosage details are as follows:

DoseSingle DoseFrequencyRouteInstructions
Adult Dosage
1.5 %1.5 %POas sterile solution of glycine in water as an irrigont.
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

None recorded.

Side Effects

Glycine in overdosage may give rise to further complications which include Pulmonary toxicity , Cardiovascular toxicity , Hyperammonemia.

Glycine is known to cause more or less tolerable side effects which are usually transient. These include Electrolyte imbalance.

Warnings / Precautions

Glycine should be used with caution in patients with liver impairment. Avoid use in patients with anuria.Hepatic impairment as any absorption and consequent metabolism may cause hyperammonaemia. Cardiopulmonary dysfuntion . CV status before and during treatment in pateints with cardiac disease.

Available Brands

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Single Ingredient

Multi-Ingredient Combinations

Storage Conditions

Glycine should be stored Irrigation soln.

Drug Classification

  1. 1.26.2.3Glycine preparations

Manufacturers

Manufacturers of Glycine in Pakistan: