Phenazone
Also known as: Antipyrine
Phenazone is antipyretic, analgesic, reduces fever and relieves pain. Phenazone is used topically as a local anesthetic. Phenazone is rarely used, often found in analgesic mixtures and in otic (ear) preparations.
Primary Characteristics
Phenazone is also known as Antipyrine.
It is of Synthetic origin and belongs to Pyrazolin.
Molecular Weight: 188.2 · pKa: 1.4 · Solubility in Water: freely · Solubility in Alcohol: freely · Non-proprietary name: Phenazone.
Pharmacokinetics
Distribution: Phenazone has a plasma protein binding is < 10 %.
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Indications
Phenazone is primarily indicated in conditions like Inflammation, Otitis media, Pain.
Contraindications
Phenazone is contraindicated in conditions like Hypersensitivity to the drug.
Dosage
Phenazone's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 3 drops | 3 drops | Every 6h | Otic | |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Phenazone in overdosage may give rise to further complications which include Hemolytic anemia , Hemolytic anemia , Hypersensitivity reactions , Porphyria.
Phenazone produces potentially life-threatening effects which include Coma, Convulsions . Careful monitoring is needed with proper medical management.
Phenazone is known to cause more or less tolerable side effects which are usually transient. These include Drowsiness, Nausea, Skin eruptions.
Warnings / Precautions
Available Brands
Click on a strength to view available brands.
Multi-Ingredient Combinations
Storage Conditions
Drug Classification
- 1.28 — Otic drugs
Manufacturers
Manufacturers of Phenazone in Pakistan: