Phenazopyridine (HCl)

Drug #1251

Phenazopyridine (HCl) is azo dye that exerts an analgesic effect on the mucosa of urinary tract and is used to provide relief of pain, burning and irritabilty in conditions such as cystitis and prostatitis. Given in combination with antibacterial in urinary tract infections.

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Primary Characteristics

It is of Synthetic origin.

Molecular Weight: 249.7 · Solubility in Water: 1 in 300 · Solubility in Alcohol: 1 in 59 · Non-proprietary name: Phenazopyridine (HCl).

Molecular structure of Phenazopyridine (HCl)

Pharmacokinetics

Elimination: renal excretion is 65 % (unchanged).

Indications

Phenazopyridine (HCl) is primarily indicated in conditions like Surgery, Trauma, UTI.

Contraindications

Phenazopyridine (HCl) is contraindicated in conditions like Hepatitis, Renal insufficiency.

Dosage

Phenazopyridine (HCl)'s dosage details are as follows:

Dose	Single Dose	Frequency	Route
Adult Dosage
200 mg	200 mg	Every 8h	PO
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

None recorded.

Side Effects

Phenazopyridine (HCl) in overdosage may give rise to further complications which include Hepatotoxicity , Hemolytic anemia , Methemoglobinemia , Meningitis .

Phenazopyridine (HCl) produces potentially life-threatening effects which include Renal failure. Careful monitoring is needed with proper medical management.

The signs and symptoms that are produced after acute overdosage of Phenazopyridine (HCl) are Methemoglobinemia, Hemolytic anemia, Renal toxicity, Hepatic toxicity.

Phenazopyridine (HCl) is known to cause more or less tolerable side effects which are usually transient. These include GI disturbance, Headache, Rashes .

Warnings / Precautions

Use phenazopyridine with caution in patients with kidney or liver disease, during pregnancy or lactation. Phenazopyridine can interfere with laboratory tests, including urine tests for glucose (sugar) and ketones, before having any tests, tell the laboratory personnel and doctor about taking this medication. Diabetics should use Clinitest to test their urine for sugar because phenazopyridine does not affect the results. Do not wear contact lenses while taking this medication, because phenazopyridine may cause staining of contact lenses.

Interference in Pathology

Phenazopyridine (HCl) may interfere in the diagnosis of Colorimetric lab. test.

Available Brands

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Single Ingredient

Tabs

100 mg

Storage Conditions

Phenazopyridine (HCl) should be stored Tab.

Drug Classification

1.1.5 — Analgesics and opioid antagonists

Manufacturers

Manufacturers of Phenazopyridine (HCl) in Pakistan:

Biogen Ontech Valor