Menthol
Menthol is alcohol obtained from diverse mint oils or prepared synthetically i.e., derived from the destructive distillation of wood. Chemically Menthol is identified as cyclohexanol, 5-methyl-2-(1-methylethyl). In low concentrations, it selectively stimulates the sensory nerve endings for cold and hence causes a sensation of coolness. Some local analgesic effect also accompany this effect.The local analgesic and the sensation of coolness are employed in the treatment of insect bites and stings, itching, hemorrhoids,cold sores, sore throat. Menthol is also incorporated into irritant products used to treat acne, dandruff, wart, corns.
Primary Characteristics
It is of Synthetic&Natural origin.
Molecular Weight: 156.3 · Solubility in Water: Insoluble · Solubility in Alcohol: very soluble · Non-proprietary name: Menthol.

Pharmacokinetics
None recorded.
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Indications
Menthol is primarily indicated in conditions like Bronchitis, Cold, Cough, Headache, Insect bites, Nasal congestion, Pruritus, Sinusitis, Sore throat, Sunburn, Urticaria.
Menthol is also indicated for secondary conditions like Acne vulgaris, Corns, Dandruff, Itching, Seborroeic conditions, Warts.
Contraindications
Menthol is contraindicated in conditions like Seizures, Hypersensitivity to murine proteins.
Dosage
None recorded.
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Menthol in overdosage may give rise to further complications which include Contact dermatitis , Apnea, Nystagmus .
Menthol produces potentially life-threatening effects which include Coma. Careful monitoring is needed with proper medical management.
The signs and symptoms that are produced after acute overdosage of Menthol are Irregularities in heart rhythm.
Menthol is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Ataxia, Drowsiness, Nausea and vomiting, Vertigo.
Warnings / Precautions
Available Brands
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Multi-Ingredient Combinations
Storage Conditions
Drug Classification
- 1.25.3 — Chest rubs and aromatic inhalants
- 2.25.5 — Pharyngeal preparations
Manufacturers
Manufacturers of Menthol in Pakistan: