DrugInfoSys

Oxethazaine

Drug #1207

Oxethazaine is amide anesthetic, witha prolong duration of action. Oxethazaine is designated as N, N-bis-(N-methyl-N-phenyl-butyl-acetamide)-betahydroxyethylamine. Oxethazaine is given by mouth along with antacid for the symptomatic relief of gastro-oesophageal reflux disease. Oxethazaine is also used in the ointments and suppositories for the relief of pain associated with haemorrhoids.

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Primary Characteristics

It belongs to Phenyl Acetamide.

Molecular Weight: 467.6 · Solubility in Water: practically Insoluble · Solubility in Alcohol: freely soluble · Non-proprietary name: Oxethazaine.

Molecular structure of Oxethazaine

Pharmacokinetics

None recorded.

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Indications

Oxethazaine is primarily indicated in conditions like Esophagitis, Oesopghagitis, Reflux oesophagitis.

Oxethazaine is also indicated for secondary conditions like Haemorrhoids, Hemorrhoids.

Contraindications

Oxethazaine is contraindicated in conditions like Hypersensitivity to any component of product.

Dosage

Oxethazaine 's dosage details are as follows:

DoseSingle DoseFrequencyRouteInstructions
Adult Dosage
7.5 mg7.5 mgEvery 8hPO
Paediatric Dosage (20kg)
0 – 0——Not recommended for this age group
Neonatal Dosage (3kg)
0 – 0——Not recommended in this age group

Drug Interactions

3 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

The signs and symptoms that are produced after acute overdosage of Oxethazaine are Drowsiness, Dizziness, Fainting .

Oxethazaine is known to cause more or less tolerable side effects which are usually transient. These include Glossitis, Hypersensitivity reactions, Idosyncratic rashes, Pruritus .

Warnings / Precautions

The use of magnesium-containing antacids in patients with mild to moderate renal impairment should be carefully monitored due to a possible increased danger of hypermagnesemia. Hypophosphatemia may occur with prolonged administration or large doses of aluminum-containing antacids (except aluminum phosphate) especially in patients with an inadequate dietary intake of phosphorus.

Interference in Pathology

Oxethazaine may interfere in the diagnosis of Monitoring of Serum phosphate levels.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Susp
10 mg10 mg/5ml
Tabs
10 mg

Multi-Ingredient Combinations

Susp
10 mg/5ml
Tabs
10 mg

Storage Conditions

Oxethazaine should be stored Tab.

Drug Classification

  1. 1.17.1.1 — Antacids & antiflatulents
  2. 2.17.3 — Antihemorrhoidals

Manufacturers