DrugInfoSys

Glycerin

Also known as: Glycerol

Drug #1142

Glycerin is a clear, syrupy liquid obtained as a by-product of soap, by carbohydrate fermentation and by propylene synthesis. Glycerin is administered rectally and orally. Glycerin is used topically for its softening and water retaining properties and also in constipation as a stool softener.

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Primary Characteristics

Glycerin is also known as Glycerol.

It belongs to Propanetriol.

It is classified in Emollient pharmacological group. It is also classified under Diuretics .

Molecular Weight: 92.09 · Solubility in Water: miscible · Solubility in Alcohol: miscible · Non-proprietary name: Glycerin · pH: 5.9 · Isotonic value: 2.6.

Molecular structure of Glycerin

Pharmacokinetics

Elimination: it is metabolised via Liver, renal excretion is major.

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Indications

Glycerin is primarily indicated in conditions like Constipation, Dry skin, Skin diseases, Sore throat.

Contraindications

Glycerin is contraindicated in conditions like Nausea and vomiting, Anuria, Intestinal obstruction, Pulmonary edema.

Dosage

Glycerin's dosage details are as follows:

DoseSingle DoseFrequencyRouteInstructions
Adult Dosage
1 – 5 ml——POSpoon fuls of liquid repeat after4 hours
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

Unknown1 interaction
1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Glycerin is known to cause more or less tolerable side effects which are usually transient. These include Abdominal cramps, Bloating , Confusion, Diarrhea, Dizziness, Fall in BP , Flatulence, Headache, Irregular heart beat, Nausea and vomiting, Ocular irritation and pain, Severe Dehydration, Thirst, Weakness.

Warnings / Precautions

Glycerine should be used with caution in patients of hypervolemia, confused mental state, congestive heart disease, diabetic patients and dehydrated individuals, Pregnancy.

Interference in Pathology

Glycerin may interfere in the diagnosis of None well documented.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Liquid
10 %w/v85 %w/v
Liquid
100 %w/v
Oint
10 %w/w
Soln
10 %w/v

Multi-Ingredient Combinations

Ear Drops
30 %v/v
Enema
90 %90 %v/v
Eye Drops
0.2 %w/v
Inf
2.21 %w/v
Inf
2.5 %w/v
Linctus
750 mg/5ml
Liquid
50 ml/100ml90 %w/v
Mouth Wash
10 %w/v
Poultice
425 g/kg
Soln
100 mg/5ml

Storage Conditions

Glycerin should be stored Liq. Suppositories.

Drug Classification

  1. 1.13.8 — Emollients & protectives
  2. 2.17.6 — Laxatives

Manufacturers