Vinpocetine
Vinpocetine is used in the treatment of cerebro-vascular and cognitive disorders.
Primary Characteristics
It is of origin and belongs to Apovincaminoate .
It belongs to Anticonjuctivitis pharmacological group on the basis of mechanism of action and also classified in Ergot Alkaloid pharmacological group.
Molecular Weight: 350.5 · Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Vinpocetine.
Pharmacokinetics
Distribution: Vinpocetine has a volume of distribution is . plasma protein binding is .
Elimination: it is metabolised via , plasma half-life is , renal excretion is .
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Indications
Vinpocetine is primarily indicated in conditions like Arteriosclerosis, Cerebral ischaemia, Macula degeneration, Vasospasm.
Vinpocetine is also indicated for secondary conditions like Hearing loss.
Contraindications
None recorded.
Dosage
Vinpocetine's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 5 g | 5 g | Every 24h | PO | |
| 20 mg | 20 mg | Every 24h | Slow IV | |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Vinpocetine is known to cause more or less tolerable side effects which are usually transient. These include Hypotension , Immature beats, Tachycardia.
Available Brands
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Single Ingredient
Storage Conditions
Drug Classification
- 1.24.6 — Cerebrovascular drugs
Manufacturers
Manufacturers of Vinpocetine in Pakistan: