Typhoid Vaccine

Drug #1093

Typhoid Vaccine is a freeze dried preparation of live Salmonella typhi strain grown in a suitable medium. Typhoid Vaccine is indicated for active immunisation to prevent typhoid fever in persons who are at risk.

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Primary Characteristics

It is of Semi Synthetic origin.

It is classified in Vaccines , Vaccines pharmacological group. It is also classified under Toxoids .

Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Typhoid Vaccine.

Pharmacokinetics

None recorded.

Indications

Typhoid Vaccine is primarily indicated in conditions like Typhoid prophylaxis.

Contraindications

Typhoid Vaccine is contraindicated in conditions like Hypersensitivity.

Dosage

Typhoid Vaccine's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
25 ug	25 ug	—	IM	(or 0.5ml).Once or As Required.
Paediatric Dosage (20kg)
0.25 ml	0.25 ml	—	Intra Muscular	Per month for 2 Months
0.25 ml	0.25 ml	—	Subcutaneous	Per month for 2 Months
Neonatal Dosage (3kg)
No data.

Drug Interactions

2 interactions

Moderate1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Typhoid Vaccine in overdosage may give rise to further complications which include Anaphylactoid reactions .

Typhoid Vaccine is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Diarrhea, Erythema, Fever, General aches, Headache, Itching, Malaise, Myalgia, Nausea, Pain , Redness, SwellingX, Vomiting .

Warnings / Precautions

Vaccine should be used with caution in patients with any illness, infection, allergy or if patients receiving radiation therapy. It should be used during pregnancy or lactation only if clearly needed. The vaccine should be postponed in subjects suffering from acute fibrile illness. The vaccine protects against typhoid fever caused by Salmonella typhi. Protection is not conferred against parathyroid fever or illness caused by non-invasive Salmonellae. Vaccine has not been evaluated in children under 2 years of age. Nevertheless, it is known that the children under this age may show a sub-optimal response to polysaccharide antigen vaccines. The decision to use the vaccine in this age group should be based upon the risk of exposure to disease. Appropriate medical treatment and supervision should always be readily available in case of a rare anaphylactic reactions following the administration of the vaccine.Typhoid vaccine under no circumtances be administered intravenously.

Available Brands

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Single Ingredient

Inj

1000 mil/ml 25 mcg/0.5ml 500 mil/0.5ml

Storage Conditions

Typhoid Vaccine should be stored Inj.

Drug Classification

1.19.3.2 — Vaccines for specific groups of individuals

Manufacturers

Manufacturers of Typhoid Vaccine in Pakistan:

Amson Aventis GENE-TECH LABS GSK Hakimsons HI-WARBLE