Tulobuterol (HCl)

Drug #1092

Tulobuterol (HCl) is a bronchodilator, similar to salbutamol. Tulobuterol (HCl) is used prophylactially in reversible obstructive air way disease.

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Primary Characteristics

It is of origin and belongs to Phenylethanol .

It belongs to Beta-2 adrenergic agonist pharmacological group on the basis of mechanism of action and also classified in Bronchodilator pharmacological group.

Molecular Weight: 264.2 · Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Tulobuterol HCl.

Molecular structure of Tulobuterol (HCl)

Pharmacokinetics

Distribution: Tulobuterol (HCl) has a volume of distribution is . plasma protein binding is .

Elimination: it is metabolised via , plasma half-life is , renal excretion is .

Indications

Tulobuterol (HCl) is primarily indicated in conditions like Asthma, Bronchospasm, Chronic bronchitis, Emphysema.

Contraindications

None recorded.

Dosage

Tulobuterol (HCl)'s dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
1 mg	1 mg	Every 12h	PO
Paediatric Dosage (20kg)
0.03 mg/kg	0.03 mg/kg	Every 12h	Oral	Recommended for 6-12 Yrs of Children
Neonatal Dosage (3kg)
No data.

Drug Interactions

None recorded.

Side Effects

Tulobuterol (HCl) in overdosage may give rise to further complications which include Angina , CNS stimulation, Hypertension .

Tulobuterol (HCl) is known to cause more or less tolerable side effects which are usually transient. These include Headache, Insomnia, Palpitation, VertigoX, Vomiting .

Warnings / Precautions

Use with caution in the patient with diabetes mellitus, hypertension and hyperthyroidism. As with other sympathomimetic bronchodilators agents, tulobuterol should be administered cautiously to cardiac patient, espacially those with associated arrhythmias or coronary insufficiency. The concomitant systemic use of tulobuterol with other combined effect on the cardiovascular system may be deleterious to the patient. Tolubuterol should not be prescribed together with beta-blocking agents. Although an intravenous injection of a cardio-selective beta-blocking agent can be given as an specific antidote for tulobuterol over dosage, the agents should be used with caution in the patients with bronchospasm.

Available Brands

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Single Ingredient

Syrup

1 mg/5ml

Tabs

1 mg 2 mg

Storage Conditions

Tulobuterol (HCl) should be stored .

Drug Classification

1.25.1.1 — Oral/Parenteral antiasthmatics

Manufacturers

Manufacturers of Tulobuterol (HCl) in Pakistan:

Abbott