Silymarin
Silymarin is the active principle from the fruit of Silybum marianum. Silymarin is a free radical scavenger, used for the treatment of hepatic disorders.
Primary Characteristics
It belongs to Chromanones.
It is also classified under Cholagogues .
Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Silymarin.
Pharmacokinetics
Elimination: renal excretion is 80 %.
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Indications
Silymarin is primarily indicated in conditions like Hepatitis, Hepatitis A infection, Jaundice.
Silymarin is also indicated for secondary conditions like Cirrhosis.
Contraindications
Silymarin is contraindicated in conditions like Hepatic encephalopathy, Primary biliary cirrhosis, Hypersensitivity to any component of product.
Dosage
Silymarin's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 200 mg | 200 mg | Every 12h | PO | |
| Paediatric Dosage (20kg) | ||||
| 30 mg/kg | 30 mg/kg | Every 12h | Oral | |
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
The signs and symptoms that are produced after acute overdosage of Silymarin are Diarrhea.
Silymarin is known to cause more or less tolerable side effects which are usually transient. These include Headache, Joint pain, Stomach upset, Weakness.
Warnings / Precautions
Available Brands
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Single Ingredient
Multi-Ingredient Combinations
Storage Conditions
Drug Classification
- 1.17.9 — Cholagogues & hepatic preparations