Secnidazole
Secnidazole is antiprotozoal, and a derivative of 5-nitromidazole closely related to metronidazole. Secnidazole is used in the treatmen of amoebiasis, giardiasis, and trichomoniasis.
Primary Characteristics
It is of Synthetic origin and belongs to Nitroimidazole.
It is classified in Amebicides pharmacological group.
Molecular Weight: 185.2 · Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Secnidazole.
Pharmacokinetics
Elimination: plasma half-life is 20 hr, renal excretion is 50 %.
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Indications
Secnidazole is primarily indicated in conditions like Amoebiasis, Giardiasis, Trichomoniasis, Urethritis, Vaginitis.
Contraindications
Secnidazole is contraindicated in conditions like Hypersensitivity to any component of product.
Dosage
Secnidazole's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 2 g | 2 g | Every 24h | PO | In invasive ( hepatic) amoebiasis , a dose of 1.5g daily in single or divided doses for 5days |
| Paediatric Dosage (20kg) | ||||
| 30 mg/kg | 30 mg/kg | — | Oral | For Once |
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Secnidazole in overdosage may give rise to further complications which include Leucopenia.
Secnidazole is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Dizziness, Glossitis, Paresthesias, StomatitisX, Taste disturbances, Urticaria.
Warnings / Precautions
Available Brands
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Single Ingredient
Storage Conditions
Drug Classification
- 1.6.4.1 — Antiamebic & antigiardiasis drugs