DrugInfoSys

Pygeum africanum

Pygeum africanum

Pygeum africanum belongs to Rosaceae family.

The English name for this herb is Pygeum .

Warning: Constipation, diarrhea or nausea may occur. If any of these effects persist or worsen, contact your doctor promptly. If you notice other effects not listed above, contact your doctor or pharmacist. Caution is advised if you have diabetes, alcohol dependence or liver disease. Ask your doctor or pharmacist about the safe use of this product. Pygeum is not recommended for use in women. It should not be used during pregnancy. Because of the potential risk to the infant, breast-feeding while using this product is not recommended. Consult your doctor before breast-feeding.

Description

Pygeum africanum. Pygeum africanum is an evergreen species found across the entire continent of Africa at altitudes of 3,000 feet or higher. It grows up to 150 feet tall

Pharmacological Actions

The pharmacological action of Pygeum africanum is Anti-inflammatory.

Indications

The indication of Pygeum africanum is Bengin prostatic hyperplasia.

Contraindications

None recorded.

Temperament

None recorded.

Occurrence, Taste & Odor

None recorded.

Dosage

PartDoseInstructions
Bark50.000 – 100.000 mg/dayTwice daily.

Available Brands

None recorded.

Compound Preparations

No Compound Preparation information is available for Pygeum africanum.

Substitutes

No information regarding Pygeum africanum's substitute is currently available.

Active Constituents

The active constituents of Pygeum africanum are Ferulic acid nesters, Pentacyclic triterpenes, Phytosterols.

Antidotes

No information regarding Pygeum africanum's antidote is currently available.

Toxicity

Pygeum africanum

Toxicological studies have shown very good tolerability after oral administration. Administration of Pygeum to dog and rat subjects equivalent to 560 times the therapeutic dose for six-month periods resulted in no adverse effects on hematological, biochemical, or anatomical/ pathological parameters. The extract had no effect on fertility in male rats and rabbits at doses up to 80 mg/kg/day -- a safety margin of 50 times the therapeutic dose. Furthermore, in vivo and in vitro mutagenicity studies showed a complete absence of mutagenic or clastogenic potential. In fact, many of the constituents of Pygeum have anticarcinogenic and antimutagenic properties in vitro and in vivo.