DrugInfoSys

Rabies Immune Globulin

Drug #991

Rabies Immune Globulin is a liquid or freeze dried preparation containing human globulins, mainly immunoglobulin G (IgG). Rabies Immune Globulin is obtained from plasma of donors immunised agianst rabies and contains specific antibodies that neutralise the rabies virus. Rabies Immune Globulin is used for passive immunization indicated for persons suspected of exposure to rabies specially in case of severe exposure.

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Primary Characteristics

It is of Natural origin and belongs to Globulins.

It is classified in Immune Globulin pharmacological group. It is also classified under Rabies Prophylaxis Products .

Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Rabies Immune Globulin (Human) · pH: 6.4.

Molecular structure of Rabies Immune Globulin

Pharmacokinetics

None recorded.

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Indications

Rabies Immune Globulin is primarily indicated in conditions like Rabies prophylaxis.

Contraindications

Rabies Immune Globulin is contraindicated in conditions like Hypersensitivity to any component of product.

Dosage

Rabies Immune Globulin 's dosage details are as follows:

DoseSingle DoseFrequencyRouteInstructions
Adult Dosage
20 IU/ kg20 IU/ kg—IMSingle dose. If possible part of the dose should be infiltered around the wound.
Paediatric Dosage (20kg)
20 IU/kg20 IU/kgEvery 24hIntra Muscular When Required
Neonatal Dosage (3kg)
No data.

Drug Interactions

2 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Rabies Immune Globulin in overdosage may give rise to further complications which include Anaphylactoid reactions .

Rabies Immune Globulin is known to cause more or less tolerable side effects which are usually transient. These include Angioedema, Fever, Muscle soreness, Soreness , Stiffiness, Urticaria.

Warnings / Precautions

Avoid IV administration of this preparation and give IM with caution in patient with thrombocytopenia and coagulopathies. Caution should be done in patients with hypersensitivity reactions to immune globulin or thimerosal.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Inj
150 IU/ml200 IU/ml

Storage Conditions

Rabies Immune Globulin should be stored IM Inj.

Drug Classification

  1. 1.19.2.5 — Rabies immunoglobulins (human)

Manufacturers

Manufacturers of Rabies Immune Globulin in Pakistan:

AventisHakimsonsIBLNationalPopular Int.