Di-Iodohydroxyquinoline
Also known as: Diodoxyquinoline
Di-iodohydroxyquinoline used in the treatment of amebiasis (dysentry) and also as an skin antiseptic.
Primary Characteristics
Di-Iodohydroxyquinoline is also known as Diodoxyquinoline.
It is of Synthetic origin and belongs to Iodoquinolone.
It is classified in Amebicides pharmacological group.
Molecular Weight: 397 · Solubility in Water: insoluble · Solubility in Alcohol: sparingly soluble · Non-proprietary name: Di-Iodohydroxyquinoline.
Pharmacokinetics
Elimination: renal excretion is <10%.
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Indications
Di-Iodohydroxyquinoline is primarily indicated in conditions like Amoebiasis, Amoebic liver abscess, Giardiasis.
Contraindications
Di-Iodohydroxyquinoline is contraindicated in conditions like Thyroid disease, Blood dyscrasias, Optic neuropathy, Nervous disorders.
Dosage
Di-Iodohydroxyquinoline's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 650 mg | 650 mg | Every 8h | PO | For 15-20 Days |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Di-Iodohydroxyquinoline in overdosage may give rise to further complications which include Thrombocytopenia , Neutropenia , Hair loss , Dermatitis .
Di-Iodohydroxyquinoline is known to cause more or less tolerable side effects which are usually transient. These include Abdominal discomfort, Ataxia, Cystitis, Diarrhea, Dizziness, Drowsiness, Dysuria, Headache, Metallic taste, Nausea, Polyuria, Pruritus , Urticaria, Vomiting .
Warnings / Precautions
Available Brands
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Multi-Ingredient Combinations
Storage Conditions
Drug Classification
- 1.6.4.1 — Antiamebic & antigiardiasis drugs