Co-Proxamol

Drug #866

Co-Proxamol contains dextropropoxyphene (which is used to relieve mild to moderate pain) and paracetamol (which is used to relieve mild to moderate pain and fever) in a fixed ratio.

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Primary Characteristics

Co-Proxamol is also known as co-codamol.

It is of Synthetic origin and belongs to opaids/analgesic.

It belongs to Cyclo-oxygenase inhibitor pharmacological group on the basis of mechanism of action. It is also classified under Analgesics and Anti-inflammatory Agents .

Molecular Weight: 299 · Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Co-Proxamol.

Pharmacokinetics

Elimination: plasma half-life is 12hr.

Indications

Co-Proxamol is primarily indicated in conditions like Mild to moderate pain.

Contraindications

Co-Proxamol is contraindicated in conditions like Alcohol dependence, Pregnancy, Hypersensitivity to any component of product.

Dosage

Co-Proxamol's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
9.285 mg/kg	9.285 mg/kg	Every 8h	PO	1 or 2 tablets every 4 to 6 hours when required for pain relief
Paediatric Dosage (20kg)
0 – 0	—	—		should not be used under 12 years
Neonatal Dosage (3kg)
No data.

Drug Interactions

None recorded.

Side Effects

Co-Proxamol in overdosage may give rise to further complications which include Coma , Blood disorders , blood disorders, slow brathing rate, inflamation of pancreas, slow heart beat, stomach pain, clammy stin, low blood pressure, Liver damage , inflamation if pancreas.

Co-Proxamol produces potentially life-threatening effects which include Hypotension, hypothyroidism, Alcoholic liver disease, gaulluadden disease. Careful monitoring is needed with proper medical management.

Co-Proxamol is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Constipation , Dizziness, Dysphoria , Euphoria, Hallucination , Headache, Jaundice , Light headedness, Nausea, Rashes , Sedation , Vision disturbances, Vomiting , Weakness.

Warnings / Precautions

Co-proxamol should be used with caution in patients with hepatic or renal impairment since higher serum concentrations or delayed elimination may occur. Patients should be advised not to exceed the recommended dose and to avoid alcohol.

Available Brands

None recorded.

Storage Conditions

Co-Proxamol should be stored .

Drug Classification

1.2.2 — Opioid analgesics