Carteolol (HCl)

Drug #838

Carteolol (HCl) is a beta-blocking agent. It slow the heart rate and reduce hypertension (high blood pressure). Carteolol (HCl) is used in the treatment of angina (chest pain), hypertension, arrhythmias (irregular heartbeats) and in glucoma.

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Primary Characteristics

It is of Synthetic origin and belongs to Dihydroquinolin.

It is classified in Antiglaucoma pharmacological group.

Molecular Weight: 328.8 · pK_a: 9.74 · Solubility in Water: 1 in 29 · Solubility in Alcohol: 1 in 8300 · Non-proprietary name: Carteolol (HCl).

Pharmacokinetics

Absorption: Carteolol (HCl) has an oral bioavailability is 97% (±2%), pre-systemic (first-pass) metabolism accounts for 7.5% (±7.5%).

Distribution: Carteolol (HCl) has a volume of distribution is 4.05 l/kg. plasma protein binding is 15%.

Elimination: plasma half-life is 3.4-7.2 hr, renal excretion is 50 - 70%.

Indications

Carteolol (HCl) is primarily indicated in conditions like Angina pectoris, Cardiac neurosis, Essential hypertension, Glucoma, Intraocular hypertension, Sinus tachycardia, Supraventricular extrasystole, Tachyarrythmia, Tachycardic arrhythmia, Ventricular extrasystole.

Contraindications

Carteolol (HCl) is contraindicated in conditions like Asthma, Cardiogenic shock, Diabetic ketoacidosis.

Dosage

Carteolol (HCl)'s dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
0.5 mg	0.5 mg	Every 12h	Ophthalmic	-
1.5 %	1.5 %	Every 12h	Ophthalmic	drops.
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

Unknown4 interactions

Major1 interaction

Moderate1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Carteolol (HCl) in overdosage may give rise to further complications which include Torsades de pointes, Corneal punctate keratitis.

The signs and symptoms that are produced after acute overdosage of Carteolol (HCl) are Bradycardia, Hypotension.

Carteolol (HCl) is known to cause more or less tolerable side effects which are usually transient. These include Abdominal discomfort, Anisocoria, Conjunctival hyperemia, Corneal staining, Drowsiness, Eye Pain , Insomnia, Malaise, Rashes , Vision disturbances.

Warnings / Precautions

Carteolol HCl should be used with caution in patients with history of heart, kidney or liver disease, asthma, bronchitis, emphysema or other lungs disease, diabetes, hyperthyroidism or any drug allergies. Before having surgery, tell the doctor or dentist about taking a beta-blocker. This drug should be used only if clearly needed during pregnancy or lactation.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Eye Drops

1 %w/v

Eye Drops

2 %w/v

Storage Conditions

Carteolol (HCl) should be stored Tab.

Drug Classification

1.21.4.2 — Beta blockers

Manufacturers

Manufacturers of Carteolol (HCl) in Pakistan:

Ethical