Bambuterol
Bambuterol acts as a bronchodilator. Bambuterol dilates the bronchi (air passage) and used in the treatment of asthma ( respiratory tract disease characterized by bronchospasm, wheezing and difficulty in breathing). Bambuterol is the ingredient of many rectal preparations used for the symptomatic relief of haemorrhoids.
Primary Characteristics
It is of Synthetic origin.
It belongs to Beta-2 adrenergic agonist pharmacological group on the basis of mechanism of action and also classified in Long Acting Bronchodilator pharmacological group.
Molecular Weight: 403.9 · Solubility in Water: freely soluble · Solubility in Alcohol: soluble · Non-proprietary name: Bambuterol.
Pharmacokinetics
Absorption: Bambuterol has an oral bioavailability is 20%.
Elimination: plasma half-life is 13 hr.
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Indications
Bambuterol is primarily indicated in conditions like Asthma, Bronchiolitis, Bronchitis, Emphysema, Obstructive airway disease, Oedema, Oliguria due to renal failure.
Bambuterol is also indicated for secondary conditions like Endometrial cancer.
Contraindications
Bambuterol is contraindicated in conditions like Hypersensitivity.
Dosage
Bambuterol's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 15 mg | 15 mg | Every 24h | PO | Gradually Increased |
| Paediatric Dosage (20kg) | ||||
| 0.75 mg/kg | 0.75 mg/kg | Every 24h | Oral | - |
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Bambuterol in overdosage may give rise to further complications which include Tonic muscle cramps .
Bambuterol is known to cause more or less tolerable side effects which are usually transient. These include Headache, Palpitation, Tremor.
Warnings / Precautions
Available Brands
Storage Conditions
Drug Classification
- 1.25.1.1 — Oral/Parenteral antiasthmatics