Acepromazine (Maleate)
Also known as: Acetylpromazine,
Acepromazine (Maleate) is used in preparation used for the management of insomnia. Acepromazine (Maleate) is also used in veterinary medicines.
Primary Characteristics
Acepromazine (Maleate) is also known as Acetylpromazine, .
It is of Synthetic origin and belongs to Phenothiazine.
It belongs to D2 antagonist pharmacological group on the basis of mechanism of action and also classified in Phenothiazine pharmacological group. It is also classified under Psychotherapeutic Drugs .
Molecular Weight: 442.5 · pKa: 9.3 · Solubility in Water: soluble · Solubility in Alcohol: soluble · Non-proprietary name: Acepromazine (Maleate) · pH: 4.5.

Pharmacokinetics
Elimination: it is metabolised via Hepatic, plasma half-life is not avilable in human.
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Indications
Acepromazine (Maleate) is primarily indicated in conditions like Anxiety disorder, Hiccup, Insomnia, Nausea and vomiting.
Contraindications
Acepromazine (Maleate) is contraindicated in conditions like Depression, Parkinsonism, Blood dyscrasias, Bone marrow depression, Coma, Brain damage.
Dosage
Acepromazine (Maleate)'s dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 75 mg | 75 mg | — | IV,IM | As Required |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Acepromazine (Maleate) in overdosage may give rise to further complications which include Hypotension , Hypotension .
The signs and symptoms that are produced after acute overdosage of Acepromazine (Maleate) are Slow heartbeat, Low blood pressure.
Acepromazine (Maleate) is known to cause more or less tolerable side effects which are usually transient. These include Agitation , Blurred vision, Constipation , Delirium , Dry mouth, Mydriasis, Nasal congestion .
Warnings / Precautions
Available Brands
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Single Ingredient
Storage Conditions
Drug Classification
- 1.17.2 — Antiemetics & antinauseants
- 2.24.3 — Drugs used in anxiety and sleep disorders
Manufacturers
Manufacturers of Acepromazine (Maleate) in Pakistan: