DrugInfoSys

Acepromazine (Maleate)

Also known as: Acetylpromazine,

Drug #778

Acepromazine (Maleate) is used in preparation used for the management of insomnia. Acepromazine (Maleate) is also used in veterinary medicines.

Primary Characteristics

Acepromazine (Maleate) is also known as Acetylpromazine, .

It is of Synthetic origin and belongs to Phenothiazine.

It belongs to D2 antagonist pharmacological group on the basis of mechanism of action and also classified in Phenothiazine pharmacological group. It is also classified under Psychotherapeutic Drugs .

Molecular Weight: 442.5 · pKa: 9.3 · Solubility in Water: soluble · Solubility in Alcohol: soluble · Non-proprietary name: Acepromazine (Maleate) · pH: 4.5.

Molecular structure of Acepromazine (Maleate)

Pharmacokinetics

Elimination: it is metabolised via Hepatic, plasma half-life is not avilable in human.

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Indications

Acepromazine (Maleate) is primarily indicated in conditions like Anxiety disorder, Hiccup, Insomnia, Nausea and vomiting.

Contraindications

Acepromazine (Maleate) is contraindicated in conditions like Depression, Parkinsonism, Blood dyscrasias, Bone marrow depression, Coma, Brain damage.

Dosage

Acepromazine (Maleate)'s dosage details are as follows:

DoseSingle DoseFrequencyRouteInstructions
Adult Dosage
75 mg75 mgIV,IMAs Required
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

4 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Acepromazine (Maleate) in overdosage may give rise to further complications which include Hypotension , Hypotension .

The signs and symptoms that are produced after acute overdosage of Acepromazine (Maleate) are Slow heartbeat, Low blood pressure.

Acepromazine (Maleate) is known to cause more or less tolerable side effects which are usually transient. These include Agitation , Blurred vision, Constipation , Delirium , Dry mouth, Mydriasis, Nasal congestion .

Warnings / Precautions

It should be used with caution in patients with peptic ulcer, in CNS disease, prostatic hypertrophy, in increased serum creatinin levels.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Storage Conditions

Acepromazine (Maleate) should be stored Tabs,Inj.

Drug Classification

  1. 1.17.2Antiemetics & antinauseants
  2. 2.24.3Drugs used in anxiety and sleep disorders

Manufacturers

Manufacturers of Acepromazine (Maleate) in Pakistan: