Metriphonate
Metriphonate is organophosphorus cholinestrase inhibitor, used as an anti infective agnent. it is used in the treatment of schistosomiasis (parasitic infection).
Primary Characteristics
It is of Natural origin and belongs to Organophosphate Ether.
It belongs to Cholinestrase inhibitor pharmacological group on the basis of mechanism of action and also classified in Cholinergic Agonist pharmacological group.
Molecular Weight: 257.5 · Solubility in Water: 1 in 7 · Solubility in Alcohol: Freely soluble · Non-proprietary name: Metriphonate.
Pharmacokinetics
None recorded.
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Indications
Metriphonate is primarily indicated in conditions like Schistosomiasis.
Contraindications
Metriphonate is contraindicated in conditions like Hypersensitivity to any component of product.
Dosage
Metriphonate's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 8.75 mg/kg | 8.75 mg/kg | — | PO | Once in 2 weeks, as required |
| Paediatric Dosage (20kg) | ||||
| 7.5 mg/kg | 7.5 mg/kg | — | Oral | Once in 2-Weeks, for 6 Weeks. |
| Neonatal Dosage (3kg) | ||||
| 7.5 mg/kg | 7.5 mg/kg | — | Oral | Once in 2-Weeks, for 6 Weeks. |
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Metriphonate is known to cause more or less tolerable side effects which are usually transient. These include Abdominal colic, Bronchospasm, Diarrhea, Dizziness, Faintness , Fatigue, Headache, Muscular weakness, Nausea and vomiting, SweatingX, Tremors, Weakness.
Warnings / Precautions
Available Brands
None recorded.
Storage Conditions
Drug Classification
- 1.6.1.1 — Intestinal anthelmintics