Lycopene

Drug #2302

Lycopene is a carotenoid responsible for the red colour of tomatoes and some other fruits including rose fruit . It is used as a colouring agent and antoxidant. Much interest has beenexpressed in the antoxidant properties of lycopene for the potential prevention of diseases such as cardiovascular disease and some cancers, particularly of the prostate gland. Lycopene is also an ingredient of some skin preparations. Lycopene is an unsaturated acyclic hydrocarbon. It contains 13 double bonds, of which 11 are conjugated. The chemical name of lycopene is 2,6,10,14,19,23,27,31 octamethyl 2,6,8,10,12,14,16,18,20,22,24,26,30-dotriacontatridecaene.

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Primary Characteristics

It is of Natural origin and belongs to Lycopene is an unsaturated acyclic hydrocarbon.

Molecular Weight: 536.9 · Solubility in Water: insoluble · Non-proprietary name: Lycopene.

Pharmacokinetics

None recorded.

Indications

Lycopene is primarily indicated in conditions like Breast cancer, Diabetes mellitus, Heart disease, Prostate cancer.

Contraindications

None recorded.

Dosage

Lycopene's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
6 mg	6 mg	—	PO	For reducing risk of Prostate cancer in womwn
6.5 mg	6.5 mg	—	PO	For reducing risk of lung cancer in non smoking women
12 mg	12 mg	—	PO	For reducing risk of lung cancer in men
30 mg	30 mg	—	PO	For decreasing the growth of prostate cancer and preventing exercise induced asthma
60 mg	60 mg	—	PO	For reducing LDL cholestrol
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

4 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Lycopene is known to cause more or less tolerable side effects which are usually transient. These include Bloating , Diarrhea, gassiness, Nausea and vomiting, Stomach irritation.

Warnings / Precautions

Pregnancy and breast-feeding: lycopene is POSSIBLY UNSAFE when taken as a supplement during pregnancy. taking 2 mg daily, starting between weeks 12 and 20 of pregnancy and continuing until delivery, increased the rate of premature births and low-birth-weight babies. Prostate cancer: lycopene might worsen established prostate cancer by increasing the spread of cancer without having any effect on cancer cell growth.

Available Brands

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Multi-Ingredient Combinations

Tabs

5 mg

Drug Classification

1.27 — Vitamins, minerals, tonics, and other susbstances

Manufacturers

Manufacturers of Lycopene in Pakistan:

GSK