Eszopiclone
Also known as: Esopiclone
This is the nonzodiapenes, hyphotic agent uesd in the treatment of Insomnia. It is the (+) isomea of zopidone
Primary Characteristics
Eszopiclone is also known as Esopiclone.
It belongs to Cyclopyrrolones.
Molecular Weight: 388.8 · Solubility in Water: Very slightly soluble · Non-proprietary name: Eszopiclone.
Pharmacokinetics
Distribution: Eszopiclone has a plasma protein binding is 52-59%.
Elimination: it is metabolised via Oxidation & demethylation, plasma half-life is 6 hr.
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Indications
Eszopiclone is primarily indicated in conditions like Insomnia.
Contraindications
None recorded.
Dosage
Eszopiclone's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 1.5 mg | 1.5 mg | — | Initially 1mg increased to 2mg | |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Eszopiclone in overdosage may give rise to further complications which include Confusion , Hoarseness , Hives, Difficulty in breathing, Rash, Swelling of the eyes, face.
The signs and symptoms that are produced after acute overdosage of Eszopiclone are Coma, Drowsiness, Drowsiness.
Eszopiclone is known to cause more or less tolerable side effects which are usually transient. These include Dizziness, Drowsiness, Dry mouth, Headache, Nausea, Rashes , Vomiting .