DrugInfoSys

Adaplene

Also known as: Adapalenum, Adapaleno

Drug #2170

Adapalene is used to treat acne. Adapalene is in a class of medications called retinoid-like compounds. It works by stopping pimples from forming under the surface of the skin.

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Primary Characteristics

Adaplene is also known as Adapalenum, Adapaleno.

It is of Synthetic origin and belongs to Naphthoic acid.

Molecular Weight: 412.58 · Non-proprietary name: Adaplene.

Molecular structure of Adaplene

Pharmacokinetics

Elimination: renal excretion is Biliary.

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Indications

Adaplene is primarily indicated in conditions like Acne, Acne vulgaris, Keratiniztion disorders, Psoriasis.

Contraindications

Adaplene is contraindicated in conditions like Eczema, Cancer, Hypersensitivity.

Dosage

Adaplene's dosage details are as follows:

DoseSingle DoseFrequencyRouteInstructions
Adult Dosage
0 – 0——TopicalAdapalene is applied once daily, after washing and before retiring. In some circumstances, when a patient complains of skin irritation, this may be decreased to once every other day until the irritation ceases.
Paediatric Dosage (20kg)
0 – 0—Every 1hTopicalApply thinly once daily in the evening
Neonatal Dosage (3kg)
0 – 0—Every 1hTopicalApply thinly once daily in evening

Drug Interactions

Minor1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Adaplene is known to cause more or less tolerable side effects which are usually transient. These include Burning, Dryness , Itching, Redness, Scales.

Warnings / Precautions

Adapalene should not be applied to skin that is sunburned, broken or covered with eczema. Avoid contact with your eyes, nose, or mouth. If contacted with eyes thoroughly wash them with plenty of water and call your doctor. Plan to avoid unnecessary or prolonged exposure to real and artificial sunlight and to wear protective clothing, sunglasses, and sunscreen with an SPF of 15 or higher, especially if you sunburn easily. Also avoid prolonged exposure to cold or wind. Adapalene may make your skin sensitive to sunlight or extreme weather. Do not use hot wax to remove unwanted hair during your treatment with adapalene.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Cream
0.1 %w/w0.1 w/w
Gel
0.1 %w/w0.1 w/w

Multi-Ingredient Combinations

Gel
0.1 %w/w

Storage Conditions

Adaplene should be stored Cream.

Drug Classification

  1. 1.13.5.1 — Antiacne preparations

Manufacturers