Nandrolone
Also known as: Nortestosterone Phenylpropionate
Nandrolone is an anabolic steroid with some androgenic properties. It is a sex hormone, with actions and adverse effects similer to testosterone. Chemically itis 17ß-[(1-oxodecyl) oxy] ester-4-en-3-one. It has androgenic,progestogenic and erythropoietic activity, but anabolic effects greater than androgenic effects. Used in treatment of debilitating illness and carcinoma of the breast. Its derivative Nandrolone (Decanoate) is given only through parentrally, not active when given orally. Nandrolone sodium sulfate has been used topically in the treatment of corneal damage.
Primary Characteristics
Nandrolone is also known as Nortestosterone Phenylpropionate, Nandrolone (Decanoate), Nandrolone Sodium Sulphate.
It is of Synthetic origin and belongs to Steroid.
It belongs to Aldosterone agonist pharmacological group on the basis of mechanism of action and also classified in Anabolic Steroid pharmacological group. It is also classified under Sex Hormones .
Molecular Weight: 274.1 · Solubility in Water: almost insoluble · Solubility in Alcohol: 1 in 1 · Non-proprietary name: Nandrolone.
Pharmacokinetics
Elimination: it is metabolised via Hepatic, plasma half-life is 5 -17 days vange 8+_5days.
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Indications
Nandrolone is primarily indicated in conditions like Anaemia, Aplastic anemia, Breast cancer, Corneal infection, Corneal injury, Corneal ulcers, Osteoporosis.
Nandrolone is also indicated for secondary conditions like Chronic debilitating disease, Renal failure, Surgery.
Contraindications
Nandrolone is contraindicated in conditions like Prostatic cancer, Male breast carcinoma.
Dosage
Nandrolone's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 100 mg | 100 mg | — | For aplastic Anaemia | |
| 62.5 mg | 62.5 mg | — | IM | Once every week. |
| 125 mg | 125 mg | — | IV | For treatment of anamia of chronic failure. |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Nandrolone in overdosage may give rise to further complications which include Deepening of voice , Stunting growth in children , liver Tumor.
Nandrolone produces potentially life-threatening effects which include Atherosclerosis . Careful monitoring is needed with proper medical management.
The signs and symptoms that are produced after acute overdosage of Nandrolone are Increased low density lipo-protein, Azoo-spermia, Increased fibrinolytic activity.
Nandrolone is known to cause more or less tolerable side effects which are usually transient. These include Abnormal LFT, Acne, Clitoromegaly , Depression, Edema, Facial hair, GI bleeding, Headache, Hypercalcemia, Impaired glucose tolerance, Increase in libido, inhibition of spermatagnesis, Menstrual irregularity, Sodium and fluid retention, Temporal recession of scalp hair.
Warnings / Precautions
Available Brands
Storage Conditions
Drug Classification
- 1.18.11 — Anabolic drugs