Moracizine
Moracizine is a phenothiazine compound with classI antiarrhythmic activity but which does not readily fall into subclasses a,b or c.
Primary Characteristics
It is of Synthetic origin and belongs to Phenothiazine compound.
Molecular Weight: 427.5 · Solubility in Water: soluble · Solubility in Alcohol: difficult · Non-proprietary name: Moracizine.
Pharmacokinetics
Distribution: Moracizine has a plasma protein binding is 95%.
Elimination: plasma half-life is 2hours, renal excretion is 56%in faeces,39%in urine.
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Indications
Moracizine is primarily indicated in conditions like Ventricular arrhythmias.
Contraindications
Moracizine is contraindicated in conditions like Myocardial infarction, Hypotension, Hypersensitivity.
Dosage
Moracizine's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 750 mg | 750 mg | — | ||
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Moracizine in overdosage may give rise to further complications which include Hallucinations , Thrombocytopenia , Allergic reactions , Bronchospasm , Hallucinations , Bronchospasm , Tremors , Myocardial infarction , Hepatic dysfunction.
Moracizine is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Cough , Dizziness, Fatigue, Fever, Headache, Hypothermia , Nausea, Skin rash.
Warnings / Precautions
Available Brands
None recorded.
Drug Classification
- 1.12.2 — Antiarrhythmic drugs