Dipivefrine

Drug #2089

Dipivefrine (HCl) is a prodrug metabolized to adrenaline. Dipivefrine (HCl) is used topically as eye drops to reduce intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension, where the prodrug passes through the cornea more readily than adrenaline.

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Primary Characteristics

Dipivefrine is also known as Dipivalyl Adrenaline (HCl), Dipivefrine (HCl).

It is of Synthetic origin and belongs to Ester.

Molecular Weight: 351.4 · Solubility in Water: very soluble · Non-proprietary name: Dipivefrine (HCl).

Pharmacokinetics

None recorded.

Indications

Dipivefrine is primarily indicated in conditions like Glaucoma, Ocular hypertension, Open-angle glaucoma.

Contraindications

Dipivefrine is contraindicated in conditions like Hypersensitivity.

Dosage

Dipivefrine's dosage details are as follows:

Dose	Single Dose	Frequency	Instructions
Adult Dosage
0.1 %	0.1 %	—	Apply every 12 hours.
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

None recorded.

Side Effects

Dipivefrine in overdosage may give rise to further complications which include Photosensitivity , Headache , Eye irritation , Blurred vision , Eye pain.

Dipivefrine is known to cause more or less tolerable side effects which are usually transient. These include Chest pain, Irregular heart beat, Tachycardia, Wheezing .

Warnings / Precautions

Care should be taken in allergic patients. If you are using other eye drops,use them 10 min apart. Donot touch the dropper.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Eye Drops

0.1 %w/v

Drug Classification

1.21.4.3 — Sympathomimetics
2.21.7 — Other ophthalmologicals

Manufacturers

Manufacturers of Dipivefrine in Pakistan:

Barrett