Phenobarbital Sodium

Also known as: Phenobarbitone Sodium

Drug #2077

Phenobarbital sodium is a barbiturate that may be used as an antiepileptic to control partial and generalized tonic-clonic seizures.

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Primary Characteristics

Phenobarbital Sodium is also known as Phenobarbitone Sodium.

Molecular Weight: 254.2 · Solubility in Water: freely soluble · Solubility in Alcohol: soluble · Non-proprietary name: Phenobarbital sodium..

Molecular structure of Phenobarbital Sodium

Pharmacokinetics

Distribution: Phenobarbital Sodium has a plasma protein binding is 45-60%.

Elimination: plasma half-life is 75-120 hours, renal excretion is through urine.

Indications

Phenobarbital Sodium is primarily indicated in conditions like Epilepsy.

Phenobarbital Sodium is also indicated for secondary conditions like Sleep disturbances.

Contraindications

Phenobarbital Sodium is contraindicated in conditions like Respiratory depression.

Dosage

Phenobarbital Sodium's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
70 mg	70 mg	—	oral	Take it at night
Paediatric Dosage (20kg)
0 – 0	—	—
Neonatal Dosage (3kg)
No data.

Drug Interactions

Unknown1 interaction

28 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Phenobarbital Sodium in overdosage may give rise to further complications which include Respiratory depression , Sedation .

The signs and symptoms that are produced after acute overdosage of Phenobarbital Sodium are Ataxia, Nystagmus.

Phenobarbital Sodium is known to cause more or less tolerable side effects which are usually transient. These include Apnea , Depression, Hypotension , Hypothermia , Restlessness.

Warnings / Precautions

It should be used with care in children and in elderly patients. Caution should also be taken in patients with renal and hepatic impairement. Donot drive while using it because it may cause drowziness.

Interference in Pathology

Phenobarbital Sodium may interfere in the diagnosis of Metyrapone Test , False +ve phentolamine test.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Inj

200 mg/2ml

Storage Conditions

Phenobarbital Sodium should be stored .

Drug Classification

1.24.1 — Drugs used in psychotic disorders

Manufacturers

Manufacturers of Phenobarbital Sodium in Pakistan:

Ameer pharma