Prajmalium Bitartarate
Prajmalium bitartarate is a class I antiarrythmic and is N-propyl derivative of Ajmaline.
Primary Characteristics
Molecular Weight: 518.6 · Non-proprietary name: Prajmalium bitartarate.
Pharmacokinetics
Elimination: plasma half-life is 5-6hours.
Advertisement
Indications
Prajmalium Bitartarate is primarily indicated in conditions like Acute myocardial infarction, Supraventricular arrhythmias.
Prajmalium Bitartarate is also indicated for secondary conditions like Tachycardia.
Contraindications
Prajmalium Bitartarate is contraindicated in conditions like Hypersensitivity, Pregnancy, Cardiogenic shock in infarction/cardiac surgery.
Dosage
Prajmalium Bitartarate's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 70 mg | 70 mg | — | oral | maintainance dose of 20-40 mg per day in divided doses should be given. |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Prajmalium Bitartarate in overdosage may give rise to further complications which include Coma , Respiratory depression , Convulsions , Agranulocytosis .
The signs and symptoms that are produced after acute overdosage of Prajmalium Bitartarate are Unconsciousness, Cardiac arrhythmias, Heart block.
Prajmalium Bitartarate is known to cause more or less tolerable side effects which are usually transient. These include Constipation , Headache, Loss of appetite, Nausea.
Warnings / Precautions
Available Brands
None recorded.
Drug Classification
- 1.12.2 — Antiarrhythmic drugs