Sissomicin Sulphate
Sissomicin sulphate is an antibiotic produced by micromonospora inyoensis and closely related to Gentamicin C1A and is an aminoglycoside.
Primary Characteristics
Molecular Weight: 1385.4 · Non-proprietary name: Sissomicin sulphate.
Pharmacokinetics
Elimination: plasma half-life is 5.16hours.
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Indications
Sissomicin Sulphate is primarily indicated in conditions like Biliary tract infections, Brucellosis, Endocarditis.
Sissomicin Sulphate is also indicated for secondary conditions like Cystic fibrosis, Endometriosis, Skin infections, Urinary tract infection.
Contraindications
Sissomicin Sulphate is contraindicated in conditions like Hypersensitivity.
Dosage
Sissomicin Sulphate's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 4.5 mg/kg | 4.5 mg/kg | — | IM | |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Sissomicin Sulphate in overdosage may give rise to further complications which include Convulsions , Muscular weakness , Respiratory depression .
The signs and symptoms that are produced after acute overdosage of Sissomicin Sulphate are Confusion , Nephrotoxicity .
Sissomicin Sulphate is known to cause more or less tolerable side effects which are usually transient. These include Hypocalcemia, Hypokalemia , Nausea and vomiting, Ototoxicity , Purpura.
Warnings / Precautions
Available Brands
None recorded.
Storage Conditions
Drug Classification
- 1.6.2.2.5 — Aminoglycosides