Bimatoprost
Bimatoprost is a synthetic prostaglandin analogue that is structurally related to dinoprost (prostaglandin F2a). It is used to reduce intra-ocular pressure in the treatment of open-angle glaucoma and ocular hypertension
Primary Characteristics
It is of Synthetic origin and belongs to prostamide analogue.
Molecular Weight: 415.58 · Solubility in Water: slightly soluble · Solubility in Alcohol: very soluble · Non-proprietary name: Bimatoprost.
Pharmacokinetics
Distribution: Bimatoprost has a plasma protein binding is 88%.
Elimination: plasma half-life is 45 hours.
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Indications
Bimatoprost is primarily indicated in conditions like Glucoma, Hypertension.
Contraindications
Bimatoprost is contraindicated in conditions like Hypersensitivity.
Dosage
Bimatoprost's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 1 eye drop | 1 eye drop | — | opthalmic | |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Bimatoprost in overdosage may give rise to further complications which include Photosensitivity .
The signs and symptoms that are produced after acute overdosage of Bimatoprost are Photophobia.
Bimatoprost is known to cause more or less tolerable side effects which are usually transient. These include Burning eyes, Dizziness, Dry eye, Eye Pain , Headache, Itching.
Warnings / Precautions
Available Brands
Storage Conditions
Drug Classification
- 1.21.4.1 — Miotics