Indocyanine Green

Drug #1932

Indocyanine Green is a dye used intravenously in determination of blood volume and flow, cardiac output and hepatic functions.

← Previous drug Next drug →

Primary Characteristics

Molecular Weight: 775 · Solubility in Water: 35 mg/ml · Solubility in Alcohol: slightly soluble · Non-proprietary name: Indocyanine Green.

Molecular structure of Indocyanine Green

Pharmacokinetics

Distribution: Indocyanine Green has a plasma protein binding is Albunim 95%.

Elimination: it is metabolised via Hepatic, plasma half-life is 150-180 seconds.

Indications

Indocyanine Green is primarily indicated in conditions like Diagnostic procedures.

Contraindications

Indocyanine Green is contraindicated in conditions like Uremia.

Dosage

Indocyanine Green's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
5 mg	5 mg	—	IV	Cardiac Arrestment.
500 mg/kg	500 mg/kg	—	IV	For testing Liver function.
Paediatric Dosage (20kg)
2.5 mg	2.5 mg	—	IV
Neonatal Dosage (3kg)
No data.

Drug Interactions

None recorded.

Side Effects

Indocyanine Green produces potentially life-threatening effects which include Tachycardia, Hypotension. Careful monitoring is needed with proper medical management.

The signs and symptoms that are produced after acute overdosage of Indocyanine Green are Anaphylactoid reactions.

Indocyanine Green is known to cause more or less tolerable side effects which are usually transient. These include Anaphylactoid reactions, Anaphylaxis, Nausea and vomiting, Urtercaria.

Warnings / Precautions

Do not dilute with solutions containing salts. Dissolve the dye as per instructions given in the leaflet. For single use only. Do not autoclave. Should be used in pregnancy only after carefully considering the benefits and risks.

Available Brands

None recorded.

Storage Conditions

Indocyanine Green should be stored Parentral.

Drug Classification

1.19.1 — Diagnostic agents