DrugInfoSys

Sodium Fluoride

Drug #1771

A dental caries prophylactic. Sodium Fluoride is used as an adjunct to diet and oral hygiene Sodium Fluoride is used in the flouridation of water and applied topically to the teeth. It may render the enamel of the teeth more resistant to acid, promote remineralization, or reduce microbial acid production.

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Primary Characteristics

It is of Synthetic origin and belongs to Sodium salts.

Molecular Weight: 42 · Solubility in Water: 1 in 25ml · Solubility in Alcohol: Practically insoluble · Non-proprietary name: Sodium Fluoride.

Molecular structure of Sodium Fluoride

Pharmacokinetics

None recorded.

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Indications

Sodium Fluoride is primarily indicated in conditions like A variety of solid tumors, Acute leukemia, Chronic lymphocytic leukaemia, Lymphomas.

Contraindications

Sodium Fluoride is contraindicated in conditions like Neonates.

Dosage

Sodium Fluoride's dosage details are as follows:

DoseSingle DoseFrequencyRouteInstructions
Adult Dosage
0.05 %0.05 %Every 24hTopical (Oral Mucosa)0.05% Sodium Fluoride = 225 ppm Fluoride
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

2 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

The signs and symptoms that are produced after acute overdosage of Sodium Fluoride are Hyperreflexia , Cardiac failure, Hyperkalemia, Tetany, Cardiac arrhythmias, Convulsions , Respiratory arrest, Tremor, Hypocalcemia, Shock, Paresthesia.

Sodium Fluoride is known to cause more or less tolerable side effects which are usually transient. These include Hypersensitivity reactions, Rashes , Skin reactions.

Warnings / Precautions

When consideration fluoride supplimentation, allowance should be made for fluorides ingested from other sources; fluoride sduppliments in children are not generally recommended when the fluoride content of drinking water is over 0.7 ppm (0.6 ppm in USA). Care should be taken to prevent children swallowing excessive fluoride after topical application to teeth. Patients with impaired renal function may be perticularly susceptible to fluorosis. Regular dialysis with fluoridated water may result in additional fluoride absorption; a maximum concentration of 0.2 ppm of fluoride in in the dialysate has been recommended. Dialysis patients not using deionised water are at risk from changes in the fluoride content of the water supply.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Oint
2 %w/w

Multi-Ingredient Combinations

Cream
2 %w/w
Mouth Wash
0.025 %w/v
Mouth Wash
0.2 g
Paste
0.1 %w/w

Drug Classification

  1. 1.17.8 — Stomatologicals and dentifrices
  2. 2.27 — Vitamins, minerals, tonics, and other susbstances

Manufacturers

Manufacturers of Sodium Fluoride in Pakistan:

HimontISISPharmevoPlatinumWebrose