Travoprost

Drug #1759

A prostaglandin analogue, it is used to reduce intra-ocular pressure in ocular hypertension or in open-angle glaucoma. Patients receiving prostaglandins should be monitored for any changes to eye coloration since an insrease in the brown pigment in the iris may occur.

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Primary Characteristics

It is of Synthetic origin.

Non-proprietary name: Travoprost.

Pharmacokinetics

None recorded.

Indications

Travoprost is primarily indicated in conditions like Ocular hypertension.

Travoprost is also indicated for secondary conditions like Sedative in combined anaesthesia.

Contraindications

None recorded.

Dosage

Travoprost's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
6 mcg	6 mcg	—	Topical (Ophthalmic)	Apply once daily.
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

None recorded.

Side Effects

Travoprost is known to cause more or less tolerable side effects which are usually transient. These include Blepharitis , Brown pigmentation particularly in those with mixed-color irides, Darkening of palpebral skin, Darkening, thickening, and lenghtening of eye lashes, Dyspnea, Exacerbation of asthma, Irritis and uveitis, Local skin reaction, Macular edema, Ocular irritation and pain, Periorbital and lid edema, Transient punctate epithelial erosions.

Warnings / Precautions

Before initiating treatment, advise patients of possible change in eye colour; monitor for eye colour change; aphakia, or pseudophakia with torn posterior lens capsule or anterior chamber lenses; risk factors for cystoid macular oedema; brittle or severe asthma; not to be used within 5 minutes of use of thiomersal-containing preparations; avoid in pregnancy and breast-feeding.

Available Brands

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Single Ingredient

Drops

40 ug

Drug Classification

1.21.4.5 — Prostaglandin analogues

Manufacturers

Manufacturers of Travoprost in Pakistan:

Bosch Novartis