Mizolastine
Mizolastine is a non-sedating antihistamine with a long duration of action. Mizolastine is a mast-cell stabilizer. Mizolastine is used for the symptomatic relief of allergic conditions including rhinitis, conjunctivitis and urticaria.
Primary Characteristics
Molecular Weight: 432.49 · Non-proprietary name: Mizolastine.
Pharmacokinetics
Distribution: Mizolastine has a plasma protein binding is 98%.
Elimination: plasma half-life is 13hr.
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Indications
Mizolastine is primarily indicated in conditions like Chronic urticaria, Rhinitis.
Contraindications
Mizolastine is contraindicated in conditions like Pregnancy, Breast feeding, Controlled hypotension in surgery.
Dosage
Mizolastine's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 10 mg | 10 mg | — | ||
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Mizolastine produces potentially life-threatening effects which include Arrhythmias. Careful monitoring is needed with proper medical management.
Mizolastine is known to cause more or less tolerable side effects which are usually transient. These include Angioedema, Antimucarinic effects, Confusion, Depression, Drowsiness, Hypersensitivity reactions, Incidence of sedation, Sleep disturbance, Weight gain.
Warnings / Precautions
Interference in Pathology
Mizolastine may interfere in the diagnosis of Raised liver enzymes.
Available Brands
None recorded.
Drug Classification
- 1.3 — Anti-allergics (Antihistamines) and drugs used in anaphylaxis