Dantron
Also known as: Danthron
Dantron is an anthraquinone stimulant laxative. Dantron is used in the treatment of constipation, but its used is now restricted only to elderly, or to terminally ill patients, because of the concern over rodent carcinogenicity.
Primary Characteristics
Dantron is also known as Danthron.
It is of Natural origin and belongs to Anthraquinones.
Molecular Weight: 240.21 · Non-proprietary name: Dantron.
Pharmacokinetics
None recorded.
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Indications
Dantron is primarily indicated in conditions like Constipation.
Contraindications
Dantron is contraindicated in conditions like Pregnancy.
Dosage
Dantron's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 8 mg | 8 mg | — | PO | For patients receiving emetogenic chemotherapy or radiotherapy: This dose should be administered 1-2 hours before treatment, followed by 8 mg orally twelve hourly. |
| 16 mg | 16 mg | — | PO | For the prevention of post-operative nausea and vomiting: This dose should be given one hour prior to induction of anaesthesia. |
| 50 mg | 50 mg | — | PO | When given as co-danthramer with poloxamer. |
| 100 mg | 100 mg | — | PO | When given as co-danthrusate with dowsate sodium. |
| Paediatric Dosage (20kg) | ||||
| 18.75 mg | 18.75 mg | — | P/O | Age 12 or above. |
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Dantron is known to cause more or less tolerable side effects which are usually transient. These include Abdominal cramps, Colored (red) urine.
Warnings / Precautions
Available Brands
None recorded.
Drug Classification
- 1.17.6 — Laxatives