Erdosteine
Erdosteine is a mucolytic that is used in the traetment of respiratory tract disorders, characterised by productive cough.
Primary Characteristics
It belongs to Mucoustic.
Molecular Weight: 249.31 · pKa: 3.71 · Solubility in Water: Slightly · Non-proprietary name: Erdosteine.
Pharmacokinetics
Distribution: Erdosteine has a plasma protein binding is 64.5%.
Elimination: it is metabolised via Hepatic, plasma half-life is 1.46+/-0.60 hrs.
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Indications
Erdosteine is primarily indicated in conditions like Acute exacerbation of chronic bronchitis.
Erdosteine is also indicated for secondary conditions like Respiratory tract disorders.
Contraindications
Erdosteine is contraindicated in conditions like Peptic ulcer, Hepatic cirrhosis with ascites, Liver damage.
Dosage
Erdosteine's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 300 mg | 300 mg | Every 2h | PO | Patients should not exceed a dose of 300 mg per day. |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Erdosteine in overdosage may give rise to further complications which include LDL high.
The signs and symptoms that are produced after acute overdosage of Erdosteine are Flushing, Sweating , Sweating, Vertigo .
Erdosteine is known to cause more or less tolerable side effects which are usually transient. These include Dermatitis, Erythema, GIT effects, Headache, Nausea, Taste alteration, Urticaria.
Warnings / Precautions
Available Brands
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Single Ingredient
Storage Conditions
Drug Classification
- 1.25.2.2 — Expectorants