Salcatonin

Also known as: Calcitonin-salmon, Salmon Calcitonin

Drug #1589

Salcatonin is a synthetic polypeptide structurally similar to natural salmon calcitonin.

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Primary Characteristics

Salcatonin is also known as Calcitonin-salmon, Salmon Calcitonin.

It is of Synthetic origin and belongs to Polypeptide.

Molecular Weight: 3431.9 · Solubility in Water: freely soluble · Non-proprietary name: Salcatonin.

Pharmacokinetics

Elimination: plasma half-life is 70-90 min.

Indications

Salcatonin is primarily indicated in conditions like Osteolysis, Osteoporosis, Pagets disease.

Salcatonin is also indicated for secondary conditions like Hypercalcaemia.

Contraindications

Salcatonin is contraindicated in conditions like Hypocalcaemia, Pregnancy, Lactation, Hypersensitivity to any component of product.

Dosage

Salcatonin's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
4 IU/kg	4 IU/kg	Every 12h	SC/IM	For hypercalcemia: If the response to this dosage is not satisfactory after 1 to 2 days, dosage may be increased up to 8 IU/kg every 12 hours. If there is no satisfactory improvement after another 2 days, dosage may be increased to a maximum of 8 IU/kg every 6 hours.
100 IU	100 IU	Every 24h	SC/IM	For paget''s disease
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

None recorded.

Side Effects

Salcatonin is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Flushing, Nausea, Rhinitis , Skin rashes, Tingling of the hand, Tremors, Unpleasant taste, Vomiting .

Warnings / Precautions

The possibility of a systemic allergic reaction should be borne in mind, and appropriate measures of treatment of a hypersensitivity reaction should be readily available. Skin testing should be considered prior to initiating salmon calcitonin therapy and the drug should not be given to patients with a positive skin test. The possibility of hypocalcemic tetany following salmon calcitonin administration should be considered, and calcium injection should be readily available, particularly during administration of the first several doses of salmon calcitonin.

Available Brands

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Single Ingredient

Inj

100 IU/ml

Nasal Spray

100 IU/actu 200 IU/actu

Storage Conditions

Salcatonin should be stored Nasal spray, Inj.

Drug Classification

1.18.14 — Drugs affecting bone metabolism

Manufacturers

Manufacturers of Salcatonin in Pakistan:

Europak Novartis