Eprosartan

Drug #1573

Eprosartan is an angiotensin-II receptor antagonist with actions, uses and adverse effects similar to those of losartan. It has been introduced more recently and is used in the treatment of hypertension. Like other memebers of this class, it may be used as an alternative to an ACE inhibitor in the management of heart failure.

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Primary Characteristics

It is of Synthetic origin and belongs to Imidazole.

Molecular Weight: 424.5 · Non-proprietary name: Eprosartan.

Pharmacokinetics

Elimination: plasma half-life is 5-9 hrs.

Indications

Eprosartan is primarily indicated in conditions like Hypertension.

Eprosartan is also indicated for secondary conditions like Diabetic nephropathy, Heart failure.

Contraindications

Eprosartan is contraindicated in conditions like Pregnancy.

Dosage

Eprosartan's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
600 mg	600 mg	Every 24h	PO	If necessary increased after 2-3 wks to 800mg QD
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

None recorded.

Side Effects

Eprosartan is known to cause more or less tolerable side effects which are usually transient. These include Angioedema, Arthralgia, Dizziness, Flatulence, Hypotension , Rarely anemia, Rhinitis .

Warnings / Precautions

Renal impairment; breast feeding; use with caution in renal artery stenosis, aortic or mitral valve stenosis and in obstructive hypertrophic cardiomyopathy.Monitor plasma-potassium concentration, particularly in elderly and in patients with renal impairment; lower initial doses may be appropriate in these patients.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Tabs

400 mg 600 mg

Storage Conditions

Eprosartan should be stored .

Drug Classification

1.12.3.4 — Angiotensin II receptor anatgonists

Manufacturers

Manufacturers of Eprosartan in Pakistan:

Abbott Wilsons