Nebivolol (HCl)
Nebivolol (HCl) is a selective beta-1 antagonist, that is used in the management of hypertension.
Primary Characteristics
It is of Synthetic origin.
Molecular Weight: 441.9 · Non-proprietary name: Nebivolol (HCl).
Pharmacokinetics
Elimination: it is metabolised via Liver, plasma half-life is 10hr, renal excretion is 98%.
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Indications
Nebivolol (HCl) is primarily indicated in conditions like Essential hypertension, Heart failure, Hypertension.
Contraindications
None recorded.
Dosage
Nebivolol (HCl)'s dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 1.25 mg/day | 1.25 mg/day | — | PO | To maximum of 10 mg once daily (instruction same as above) |
| 5 mg/day | 5 mg/day | — | PO | Initial dose which at intervals of two weaks may be increased to max of 40mg |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Nebivolol (HCl) in overdosage may give rise to further complications which include Postural hypotension .
The signs and symptoms that are produced after acute overdosage of Nebivolol (HCl) are Bradycardia, Hypotension, Bronchospasm, Cardiac insufficiency.
Nebivolol (HCl) is known to cause more or less tolerable side effects which are usually transient. These include Depression, Dizziness, Dry eye, Fatigue, Fluid retention, Headache, Nightmares, Sexual dysfunction, Shortening of breath, Skin rashes, Tiredness .
Warnings / Precautions
Available Brands
Storage Conditions
Drug Classification
- 1.12.3.1 — Beta blocking agents