Vasopressin

Drug #1481

The pressor and antidiuretic principle of the posterior lobe of the pituitary gland. It is prepared either by synthesis or by extraction from the glands of healthy domestic animals. It has a direct antidiuretic effects on the kidney, so it is used in the treatment of acute and chronic diabetes insipidus due to deficiency in antidiuretic hormone. It is administered IM, IV, SC or by nasal inhalation or topical application to the nasal mucosa.

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Primary Characteristics

It is of Natural origin.

Non-proprietary name: Vasopressin.

Pharmacokinetics

None recorded.

Indications

Vasopressin is primarily indicated in conditions like Bleeding from oesophageal varices, Diabetes insipidus, Pituitary diabetes insipidus.

Contraindications

None recorded.

Dosage

None recorded.

Drug Interactions

Unknown10 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Vasopressin in overdosage may give rise to further complications which include Cardiac arrhythmias, Bradycardia , Chest pain , Hypertension , Gangrene , Thrombosis .

Vasopressin produces potentially life-threatening effects which include Anaphylactic shock, Myocardial Ischemia , Cardiac Arrest . Careful monitoring is needed with proper medical management.

Vasopressin is known to cause more or less tolerable side effects which are usually transient. These include Cramps , Diarrhea, Headache, Hypersensitivity reactions, Nausea and vomiting, Pallor, Sweating , Tremors, Urticaria.

Warnings / Precautions

Avoid use in patients with chronic nephritis with nitrogen retension. It should be used with caution and in small doses in patients with vascular disease, especially of coronary arteries. It should be given with care to patients with asthma, migrane, epilepsy, heart failure or hypertension. Fluid retension should be adjusted to avoid hyponatremia.

Available Brands

None recorded.

Storage Conditions

Vasopressin should be stored Inj.

Drug Classification

1.10.5 — Drugs used in esophageal varices bleeding
2.18.12 — Drugs used in diabetes insipidus