DrugInfoSys

Bifemelane

Drug #1433

Bifemelane is a nootropic that has been used in the treatment of senile dementia.

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Primary Characteristics

Bifemelane is also known as Bifemelane HCl.

It is of Synthetic origin and belongs to Butanamine.

Molecular Weight: 269.38 · pKa: 9.4 · Solubility in Water: highly soluble · Solubility in Alcohol: highly soluble · Non-proprietary name: Bifemelane.

Molecular structure of Bifemelane

Pharmacokinetics

Absorption: Bifemelane has an oral bioavailability is 47.5% (±47.5%), pre-systemic (first-pass) metabolism accounts for 45% (±45%).

Distribution: Bifemelane has a volume of distribution is 8 l/kg. plasma protein binding is 95%.

Elimination: plasma half-life is 3.3 hr, renal excretion is 0.023% (unchanged).

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Indications

Bifemelane is primarily indicated in conditions like Brain dysfunction, Impaired memory.

Contraindications

None recorded.

Dosage

None recorded.

Drug Interactions

None recorded.

Side Effects

Bifemelane in overdosage may give rise to further complications which include Delirium , Convulsions .

Bifemelane is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Anorexia , Anxiety, Chest pain, Constipation , Diarrhea, Drowsiness, Dry mouth, Dyspepsia , Excitation , Headache, Heart burn, Insomnia, Nausea, Skin rashes, Taste disturbance, Vomiting .

Warnings / Precautions

Bifemelane should be used with caution in elderly and in patients with advanced hepatic disease. It should not be administered in neonates and during pregnancy and lactation. Its safety in children has not been established.

Available Brands

None recorded.

Storage Conditions

Bifemelane should be stored Tab.

Drug Classification

  1. 1.24.5 — Psychostimulants, nootropics, and neurotonics