Cinchocaine

Also known as: Dibucaine

Drug #1395

Cinchocaine is a local anesthetic. Cinchocaine is also used to treat arrhythmia (abnormal heart beat).

Primary Characteristics

Cinchocaine is also known as Dibucaine, Cinchocaine HCl, cincainum, cincaina.

It is of Synthetic origin and belongs to Amide.

Molecular Weight: 343.5 · pK_a: 8.85 · Solubility in Water: 1 in 4600 · Solubility in Alcohol: 1 in 0.7 · Non-proprietary name: Cinchocaine.

Pharmacokinetics

Elimination: it is metabolised via hepatic, plasma half-life is <1 minute.

Indications

Cinchocaine is primarily indicated in conditions like Hemorrhoids, Local anaesthesia.

Cinchocaine is also indicated for secondary conditions like Insect bites, Skin irritations, Sunburn.

Contraindications

Cinchocaine is contraindicated in conditions like Hypersensitivity to any component of product.

Dosage

Cinchocaine's dosage details are as follows:

Dose	Single Dose	Frequency	Route
Adult Dosage
0.5 %	0.5 %	Every 6h	Topical
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

None recorded.

Side Effects

Cinchocaine produces potentially life-threatening effects which include Circumoral numbness, Cardiovascular depression, Ventricular arrhythmias. Careful monitoring is needed with proper medical management.

The signs and symptoms that are produced after acute overdosage of Cinchocaine are Convulsions , Methemoglobinemia, Circulatory depression.

Cinchocaine is known to cause more or less tolerable side effects which are usually transient. These include Anxiety, Metallic taste.

Warnings / Precautions

Avoid cinchocaine in patients with known hypersensitivity. It should be given with caution to the elderly, to debilitate, to children, patients with epilepsy, impaired cardiac conduction, impaired respiratory function, shock or liver damage. It might be ototoxic and should not be instilled into the middle ear. The application of local anesthetics to the skin for prolonged period or to the extensive area should be avoided.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Inj

5 mg/ml

Storage Conditions

Cinchocaine should be stored Cream, Inj, Oint.

Drug Classification

1.1.2 — Local anesthetics

Manufacturers

Manufacturers of Cinchocaine in Pakistan:

Zafa