Sulodexide
Sulodexide is a mixture of heparin and dermatan. Sulodexide is used as a hypolipidimic (decreases the blood cholesterol and fat levels) and anti-thrombotic agent.
Primary Characteristics
It is of Synthetic origin.
Non-proprietary name: Sulodexide.
Pharmacokinetics
None recorded.
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Indications
Sulodexide is primarily indicated in conditions like Cerebrovascular disease, Thrombosis, Transient ischaemic attacks.
Sulodexide is also indicated for secondary conditions like Diabetic nephropathy, Diabetic retinopathy.
Contraindications
Sulodexide is contraindicated in conditions like Diathesis, Haemorrhagic diathesis, Hypersensitivity to any component of product.
Dosage
Sulodexide's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 1.5 cap | 1.5 cap | Every 12h | PO | For chronic cases: Should be taken 30mins before meals for 60-90days. |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Sulodexide is known to cause more or less tolerable side effects which are usually transient. These include Burning, Epigastralgia, Hematoma at the site of injection, Nausea and vomiting, Pain .
Warnings / Precautions
Available Brands
Storage Conditions
Drug Classification
- 1.12.5 — Anti-thrombotic drugs and myocardial infarction
- 2.12.6 — Lipid-regulating drugs /Anti-atheromas
Manufacturers
Manufacturers of Sulodexide in Pakistan: