Chloroform
Chloroform is an inhalation anesthetic. Chemically Chloroform is trichloromethane. It was once widely used as an anesthetis and analgesic,and as a carminative, antitussive and counter-irritant, but Chloroform is not used now-a-days due to its toxic effects. The modern discovery of the intoxicant effects of inhalants began with Sir Humphry Davy in 1799, who administered nitrous oxide himself and others. As other anesthetic gases were introduced such as it and ether, they were also used socially. Inhaled gases are the mainstay of anesthesia and are primarily used for the maintenance of anesthesia after administration of an intravenous agent. The depth of anesthesia can be rapidly altered by changing the concentration of inhaled anesthetic. Most of the agents are rapidly eliminated from the body and donot cause post-operative respirtory depression but Chloroform is used rarely due to the serious side effects it produces on heart and liver.
Primary Characteristics
Chloroform is also known as chloromethane, Trichloromrthane.
It is of Synthetic origin and belongs to Chloromethane.
Molecular Weight: 119.4 · Solubility in Water: 1 in 210 · Solubility in Alcohol: miscible · Non-proprietary name: Chloroform.

Pharmacokinetics
None recorded.
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Indications
Chloroform is primarily indicated in conditions like Anesthesia.
Contraindications
Chloroform is contraindicated in conditions like Diabetes mellitus, Sepsis.
Dosage
None recorded.
Drug Interactions
None recorded.
Side Effects
Chloroform in overdosage may give rise to further complications which include Nephrotoxicity , Cardiac arrhythmias, Hepatotoxicity , Hypotension , Cardiac arrhythmias , Hypotension , Hepatotoxicity , Decreased cardiac output .
Chloroform produces potentially life-threatening effects which include Respiratory depression, Cardiac Arrest , Cardiac arrest. Careful monitoring is needed with proper medical management.
Chloroform is known to cause more or less tolerable side effects which are usually transient. These include Blistering, Burns of skin & mucous membrane, Irritation.
Warnings / Precautions
Available Brands
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Multi-Ingredient Combinations
Storage Conditions
Drug Classification
- 1.1.1.2 — Inhalational anesthetics