Factor VII

Also known as: Proconvertin

Drug #1312

Factor VII used to treat bleeding problems in patients with haemophilia type A or B.

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Primary Characteristics

Factor VII is also known as Proconvertin.

It is of Natural origin and belongs to Amino acid.

Non-proprietary name: Factor VII · pH: 6.5 · Isotonic value: 240.

Pharmacokinetics

None recorded.

Indications

Factor VII is primarily indicated in conditions like Haemophilia, Von willebrand's disease.

Contraindications

Factor VII is contraindicated in conditions like Septicaemia, Atherosclerosis, Hypersensitivity to the drug.

Dosage

Factor VII's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
80 mcg/kg	80 mcg/kg	Every 12h	IV	Bolus injection over 2 to 5 min, then maintain hacmostaris every 2-3 hours.
270 mcg/kg	270 mcg/kg	—	IV	To treat hemarthroses:
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

None recorded.

Side Effects

Factor VII produces potentially life-threatening effects which include Anaphylaxis . Careful monitoring is needed with proper medical management.

Factor VII is known to cause more or less tolerable side effects which are usually transient. These include Diaphoresis, Fever, Headache, Nausea.

Warnings / Precautions

It should be used only if clearly needed during pregnancy.It should be used with cauiton in patients with any pre-existing diseases or any allergies. Before and during injection check heart rate.The dose or rate of infusion may need to be changed if heart rate is too fast.

Available Brands

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Single Ingredient

Inj

1.2 mg

Storage Conditions

Factor VII should be stored Powder.

Drug Classification

1.11.2 — Plasma fractions for specific use

Manufacturers

Manufacturers of Factor VII in Pakistan:

Novo