Ethamsylate
Also known as: Cyclonamin, Etamsylate
Ethamsylate hemostatic agent (prevents bleeding). Ethamsylate used to control surgical and menstrual blood loss.
Primary Characteristics
Ethamsylate is also known as Cyclonamin, Etamsylate.
It is of Synthetic origin and belongs to Sulphonates.
Molecular Weight: 263.3 · Solubility in Water: very soluble · Solubility in Alcohol: soluble · Non-proprietary name: Ethamsylate · pH: 4.5.
Pharmacokinetics
Distribution: Ethamsylate has a plasma protein binding is 90%.
Elimination: plasma half-life is 8 hrs, renal excretion is Unchanged in urine.
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Indications
Ethamsylate is primarily indicated in conditions like Haemorrhage, Short-term treatment of blood loss in menorrhagia.
Contraindications
None recorded.
Dosage
Ethamsylate's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 500 mg | 500 mg | Every 4h | For short term blood loss in menorelagia | |
| 250 – 500 mg | — | Every 6h | PO | Should be given two to three days prior to surgery, with an additional 250 to 500 milligrams (mg) several hours prior to the procedure. |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Ethamsylate in overdosage may give rise to further complications which include Hypotension , Hypotension .
Ethamsylate is known to cause more or less tolerable side effects which are usually transient. These include Headache, Nausea, Skin rashes.
Warnings / Precautions
Available Brands
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Single Ingredient
Storage Conditions
Drug Classification
- 1.10.3 — Antihemorrhagics/Antihemophilics
Manufacturers
Manufacturers of Ethamsylate in Pakistan: