Ambroxol (HCl)
Ambroxol is a metabolite of bromohexine and has similar actions and uses. Ambroxol (HCl) is used in a variety of respiratory disoreders including chronic bronchitis
Primary Characteristics
It is of Synthetic origin.
Molecular Weight: 414.6 · Solubility in Water: Slightly soluble · Solubility in Alcohol: Soluble · Non-proprietary name: Ambroxol (HCl) · pH: 4.5.
Pharmacokinetics
Elimination: it is metabolised via Liver, plasma half-life is 1-3 hour.
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Indications
Ambroxol (HCl) is primarily indicated in conditions like Bronchitis, Chronic bronchitis, Cystic fibrosis.
Contraindications
None recorded.
Dosage
Ambroxol (HCl)'s dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 30 mg/5ml | 30 mg/5ml | Every 24h | Oral | 30mg/5mL DS Syrup: 1 tsp 3 times a day. |
| 75 mg | 75 mg | Every 24h | Oral | 75 mg SR Capsule: 1 cap per day. |
| 90 mg | 90 mg | Every 8h | Oral | 30 mg tablets: 1 tab 3 times a day. |
| 375 mg/d | 375 mg/d | Every 12h | Oral | For uricosuric action, total daily dose can be given as 2 divided doses. Maximum tolerated dose is 1 g. |
| Paediatric Dosage (20kg) | ||||
| 0 – 0 | — | — | ||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Ambroxol (HCl) is known to cause more or less tolerable side effects which are usually transient. These include Contact allergy, Hypersensitivity reactions.
Warnings / Precautions
Available Brands
Storage Conditions
Drug Classification
- 1.25.1.1 — Oral/Parenteral antiasthmatics
- 2.25.2.2 — Expectorants